Taking Hydrochlorothiazide with alcohol may have additive effects in lowering blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.

Metonce H 50mg/12.5 mg Tablet XL may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Metonce H 50mg/12.5 mg Tablet XL is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Metonce H 50mg/12.5 mg Tablet XL may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

Metonce H 50mg/12.5 mg Tablet XL should be used with caution in patients with severe kidney disease. Dose adjustment of Metonce H 50mg/12.5 mg Tablet XL may be needed. Please consult your doctor.Use of Metonce H 50mg/12.5 mg Tablet XL is not recommended in patients with severe kidney disease.

Metonce H 50mg/12.5 mg Tablet XL should be used with caution in patients with liver disease. Dose adjustment of Metonce H 50mg/12.5 mg Tablet XL may be needed. Please consult your doctor.